Addison's disease can be fatal. The adrenal hormones (cortisol and aldosterone) that are diminished with Addison's Disease are necessary for maintaining normal health, including blood pressure, kidney filtration, and a strong heartbeat. Without cortisol and aldosterone, your pet will be weak and may vomit. Their heart won't beat normally; they can shake, and become dehydrated. If your pet is not treated with fluids and cortisol, he or she may die.
Pets diagnosed with Addison's Disease will generally require lifelong treatment.
Recommended pet medications for dogs and cats with Addison's disease
Percorten-V
Percorten-V (desoxycorticosterone pivalate) is the only medication approved by the FDA for treating Canine Addison's Disease (hypoadrenocorticism). Percorten-V requires a prescription from your veterinarian.
You will need a syringe to use Percorten-V, but it is not included in the package. Please see 3cc (3ml) luer slip syringe with 3/4" 25 g Needle.
For:
Dogs
Benefits:
Well tolerated
Low incidence of side effects
How it Works:
Canine Addison's Disease is a condition where a dog's adrenal glands don't work properly. Normal adrenal glands produce mineralocorticoids that help regulate many bodily functions such as metabolism, blood pressure, and stress response. Percorten-V is a replacement therapy for the mineralocorticoid deficiency in dogs with Addison's disease.
Fludrocortisone
Fludrocortisone is used by veterinarians in the treatment of Addison's Disease. Fludrocortisone requires a prescription from your veterinarian, and is sold per tablet.
For:
Cats and Dogs
Benefits:
Easy to administer
Once a day dosing, typically
How it Works:
Fludrocortisone acetate is a mineralocorticoid, similar in action to aldosterone, which acts on the kidney to help balance the concentration of sodium and potassium in your pet's body.
Prednisolone
Prednisolone is a corticosteroid used to treat various inflammatory and allergy conditions as well as other diseases. Prednisolone requires a prescription from your veterinarian, and is sold per tablet.
For:
Cats and Dogs
Benefits:
Treats a wide range of inflammatory and auto-immune conditions
Remedies swelling and itchy skin caused by allergies
Reduces redness, itching, and allergic reactions affecting the eyes
How it works:
Prednisolone is a corticosteroid, which suppresses the inflammatory response to a variety of agents. Prednisolone can also be used as an immunosuppressive drug for organ transplants and in cases of adrenal insufficiency (Addison's disease).
Read more: Addison's Disease in Dogs and Cats
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